Author/Authors :
Istv?n Borza، نويسنده , , S?ndor Kolok، نويسنده , , Anik? Gere، نويسنده , , Eva ?gai-Csongor، نويسنده , , Béla ?gai، نويسنده , , G?bor T?rk?nyi، نويسنده , , Csilla Horv?th، نويسنده , , Gizella Barta-Szalai، نويسنده , , Eva Boz?، نويسنده , , Csilla Kiss، نويسنده , , Attila Bielik، نويسنده , , J?zsef Nagy، نويسنده , , S?ndor Farkas، نويسنده , , Gy?rgy Dom?ny، نويسنده ,
Abstract :
A novel series of indole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the number and position of OH groups on the indole skeleton as well as the substitution of the piperidine ring on the biological activity of the compounds was studied.