Title of article :
11,12-Epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-α-Induced VCAM-1 expression
Author/Authors :
J. R. Falck، نويسنده , , L. Manmohan Reddy، نويسنده , , Y. Krishna Reddy، نويسنده , , Muralidhar Bondlela، نويسنده , , U. Murali Krishna، نويسنده , , Yu Ji، نويسنده , , Jianxin Sun، نويسنده , , James K. Liao، نويسنده ,
Abstract :
A series of 11,12-EET analogues were synthesized and compared using a human endothelial cell based TNF-α-induced VCAM-1 expression assay. The resulting data were used to map a putative recognition/binding domain for 11,12-EET.
