Title of article
B-Ring unsaturated estrogens: biological evaluation of 17α-Dihydroequilein and novel B-Nor-6-thiaequilenins as tissue selective estrogens
Author/Authors
Charles W. Lugar III، نويسنده , , David Magee، نويسنده , , Mary D. Adrian، نويسنده , , Pamela Shetler، نويسنده , , Henry U. Bryant، نويسنده , , Jeffrey A. Dodge، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
4281
To page
4284
Abstract
The pharmacology and SAR of representative equine estogens is described. 17α-Dihydroequilenin was found to prevent bone loss after 5 weeks of oral administration to ovariectomized rats. The stereochemical significance of the D-ring and the C/D ring juncture was investigated with a series of benzothiophene-based equilenin analogues.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793765
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