Title of article
Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects
Author/Authors
Young-Ger Suh، نويسنده , , Yong Sil Lee، نويسنده , , Kyung-Hoon Min، نويسنده , , Ok-Hui Park، نويسنده , , Ho-Sun Seung، نويسنده , , Hee-Doo Kim، نويسنده , , Hyoung-Geun Park، نويسنده , , Ji-yeon Choi، نويسنده , , Jeewoo Lee، نويسنده , , Sang-Wook Kang، نويسنده , , Uhtaek Oh، نويسنده , , Jae-yeon Koo، نويسنده , , Yung Hyup Joo، نويسنده , , Sun-Young Kim، نويسنده , , Jin-Kwan Kim، نويسنده , , Young-Ho Park، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
4389
To page
4393
Abstract
A novel non-vanilloid VR1 antagonist consisting of a new vanilloid equivalent exhibits excellent analgesic effects as well as highly potent antagonistic activities in both capsaicin single channel and calcium uptake assays. In addition, the structural requirement for the vanilloid equivalent of the potent VR1 antagonist has also been elucidated.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793787
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