Title of article
Design and SAR of thienopyrimidine and thienopyridine inhibitors of VEGFR-2 kinase activity
Author/Authors
Michael J. Munchhof، نويسنده , , Jean S. Beebe، نويسنده , , Jeffery M. Casavant، نويسنده , , Beth A. Cooper، نويسنده , , Jonathan L. Doty، نويسنده , , R. Carla Higdon، نويسنده , , Stephen M. Hillerman، نويسنده , , Catherine I. Soderstrom، نويسنده , , Elisabeth A. Knauth، نويسنده , , Matthew A. Marx، نويسنده , , Ann Marie K. Rossi، نويسنده , , Susan B. Sobolov، نويسنده , , Jianmin Sun، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
21
To page
24
Abstract
Novel classes of thienopyrimidines and thienopyridines have been identified as potent inhibitors of VEGFR-2 kinase. The synthesis and SAR of these compounds is presented, along with successful efforts to diminish EGFR activity present in the lead series.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793916
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