• Title of article

    Discovery of a novel series of DHODH inhibitors by a docking procedure and QSAR refinement

  • Author/Authors

    Johann Leban، نويسنده , , Wael Saeb، نويسنده , , Gabriel Garcia، نويسنده , , Roland Baumgartner، نويسنده , , Bernd Kramer، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2004
  • Pages
    4
  • From page
    55
  • To page
    58
  • Abstract
    A novel series of DHODH inhibitors was developed based on a lead which was obtained by a docking procedure and a medicinal chemistry exploration. The activity of the initial lead was improved by a QSAR method to yield low nanomolar inhibitors.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2004
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    793924

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=793924