Title of article
Synthesis and antitumour activity of pyrene-linked pyrrolo [2,1-c] and benzodiazepine hybrids
Author/Authors
Ahmed Kamal، نويسنده , , G. RAMESH، نويسنده , , O. Srinivas، نويسنده , , P. Ramulu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
471
To page
474
Abstract
Pyrene-linked pyrrolobenzodiazepine hybrids have been synthesized that exhibit potential anticancer activity in a number of human tumour cell lines. These hybrids also exhibit much enhanced DNA-binding ability in comparison to the parent pyrrolobenzodiazepine ring system (DC-81).
Keywords
Cytotoxity , DNAbindingaffinity. , Pyrene amine , Pyrrolobenzodiazepines
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794011
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