Title of article
Degradation of target protein in living cells by small-molecule proteolysis inducer
Author/Authors
Dong Zhang، نويسنده , , Sun-Hee Baek، نويسنده , , Abby Ho، نويسنده , , Kyungbo Kim، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
645
To page
648
Abstract
Ubiquitin-dependent proteolysis of cellular proteins is one of the major pathways to regulate protein function posttranslationally. Here we demonstrate a potentially general method of degrading any targeted proteins by the ubiquitin-dependent proteolysis in living cells, using small-molecule proteolysis inducer (SMPI).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794046
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