Title of article
Potent imidazole and triazole CB1 receptor antagonists related to SR141716
Author/Authors
Brian Dyck، نويسنده , , Val S. Goodfellow، نويسنده , , Teresa Phillips، نويسنده , , Jonathan Grey، نويسنده , , Mustapha Haddach، نويسنده , , Martin Rowbottom، نويسنده , , Gregory S. Naeve، نويسنده , , Brock Brown، نويسنده , , John Saunders، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
1151
To page
1154
Abstract
Diarylimidazolecarboxamides and diaryltriazolecarboxamides related to SR141716 were synthesized and tested for binding to the human CB1 receptor. Suitably substituted imidazoles are comparably potent to the clinical candidate, whereas the analogous triazoles are less so due to the absence of an additional substituent on the azole ring.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794149
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