Title of article
Comparison of 2-phenylspiroindenes and 2-phenylspiroindenediones as estrogen receptor ligands—modeling and binding data donʹt agree!
Author/Authors
Timothy A. Blizzard، نويسنده , , Ralph T. Mosley، نويسنده , , Elizabeth T. Birzin، نويسنده , , Wanda Chan، نويسنده , , Milton L. Hammond، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
1317
To page
1321
Abstract
A series of 2-phenylspiroindenediones was prepared. The spiroindenediones were found to be less active than the corresponding spiroindenes as estrogen receptor ligands and failed to demonstrate the receptor subtype selectivity that had been anticipated from molecular modeling.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794185
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