Author/Authors :
Fumiyo Saito، نويسنده , , Ryo Takeuchi، نويسنده , , Tomoyuki Kamino، نويسنده , , Kouji Kuramochi، نويسنده , , Fumio Sugawara، نويسنده , , Kengo Sakaguchi، نويسنده , , Susumu Kobayashi، نويسنده ,
Abstract :
We found that untenone A and mannzamenone A inhibit mammalian DNA polymerases α and β, and human terminal deoxynucleotidyl transferase (TdT). The syntheses of both compounds and the structure–activity relationships of untenone A derivatives are described.