Title of article :
Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand
Author/Authors :
Norikazu Nishino، نويسنده , , Daisuke Yoshikawa، نويسنده , , Louis A. Watanabe، نويسنده , , Tamaki Kato، نويسنده , , Binoy Jose، نويسنده , , Yasuhiko Komatsu، نويسنده , , Yuko Sumida، نويسنده , , Minoru Yoshida، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Pages :
5
From page :
2427
To page :
2431
Abstract :
Cyclic tetrapeptide retrohydroxamic acids were prepared as histone deacetylase (HDAC) inhibitors and evaluated the inhibitory activity and found that they have potential as anticancer drugs.
Keywords :
Retrohydroxamate , inhibitor , Histone deacetylase , Cyclictetrapeptide.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2004
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
794412
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=794412
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