Title of article
Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities
Author/Authors
Yurngdong Jahng، نويسنده , , Long-Xuan Zhao، نويسنده , , Yoon-Soo Moon، نويسنده , , Arjun Basnet، نويسنده , , Eunkyung Kim، نويسنده , , Hyeun Wook Chang، نويسنده , , Hye Kyung Ju، نويسنده , , Tae Cheon Jeong، نويسنده , , Eung Seok Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
2559
To page
2562
Abstract
For the development of safer anti-inflammatory agents, simple aromatic compounds containing propenone moiety were prepared and evaluated for their dual COX/5-LOX inhibitory activities. Among the 17 prepared compounds, most of the compounds exhibited considerable COX/5-LOX inhibitory activities. Especially compound C15 showed the most significant dual COX/5-LOX inhibitory activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794437
Link To Document