Title of article :
Novel 3,5-diaryl pyrazolines as human acyl-CoA:cholesterol acyltransferase inhibitors
Author/Authors :
Tae-Sook Jeong، نويسنده , , Kyung Soon Kim، نويسنده , , So-Jin An، نويسنده , , Kyung-Hyun Cho، نويسنده , , Sangku Lee، نويسنده , , Woo Song Lee، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
A series of pyrazoline derivatives were prepared for evaluating their acyl-CoA:cholesterol acyltransferase activities. 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)-5-(multi-substituted 4-hydroxyphenyl)-2-pyrazolines 4a–i were shown in vitro inhibitory activity on hACAT-1 and -2.
Keywords :
ACAT inhibitor.* Corresponding author. Tel.: +82-42-860-4278 , fax: +82-42-861-2675 , e-mail: wslee@kribb.re.kr
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
