Title of article :
Synthesis of novel fluorescent-labelled dinucleoside polyphosphates
Author/Authors :
Michael Wright، نويسنده , , Andrew D. Miller، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Pages :
4
From page :
2813
To page :
2816
Abstract :
A novel tandem synthetic–biosynthetic procedure is described for the synthesis of four new fluorescent dinucleoside polyphosphates: mant–Ap4A, mant–AppCH2ppA, TNP–Ap4A and TNP–AppCH2ppA. These compounds are expected to supplement the existing etheno (ε) and 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) labelled derivatives, being the fluorescent probes of choice to investigate polyphosphate/enzyme binding behaviour.
Keywords :
Diadenosine tetraphosphate , Mant , Ap4A , TNP , LysU. , Ap3A , synthesis , Dinucleoside polyphosphate , Fluorescent
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2004
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
794488
Link To Document :
بازگشت