Title of article
Synthesis and evaluation of spirobenzazepines as potent vasopressin receptor antagonists
Author/Authors
Min Amy Xiang، نويسنده , , Robert H. Chen، نويسنده , , Keith T. Demarest، نويسنده , , Joseph Gunnet، نويسنده , , Richard Look، نويسنده , , William Hageman، نويسنده , , William V. Murray، نويسنده , , Donald W. Combs، نويسنده , , Mona Patel، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
3
From page
2987
To page
2989
Abstract
A novel series of spirobenzazepines was synthesized and evaluated for V1a and V2 receptor antagonist activity. Compounds 8b, 8i, and 8k have shown selective V1a receptor antagonist activity. Compounds 8p and 8q were shown to be dual V1a/V2 receptor antagonists.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794524
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