Title of article
Design and synthesis of β-amino-α-hydroxy amide derivatives as inhibitors of MetAP2 and HUVEC growth
Author/Authors
Martin Sendzik، نويسنده , , James W. Janc، نويسنده , , Ronnel Cabuslay، نويسنده , , Lee Honigberg، نويسنده , , Richard L. Mackman، نويسنده , , Catherine Magill، نويسنده , , Neil Squires، نويسنده , , Nancy Waldeck، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
3181
To page
3184
Abstract
The rational design and synthesis of β-amino-α-hydroxy amide derivatives as reversible inhibitors of methionine aminopeptidase-2 (MetAP2) with anti-proliferative activity against human umbilical vein endothelial cells (HUVECs) is described.
Keywords
MetAP2 , Reversible inhibitor , HUVEC.* Corresponding author. Tel.: +1-650-866-6533 , Angiogenesis , fax: +1-650-866-6655 , e-mail: martin.sendzik@celera.com
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794561
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