Title of article :
Simple and an efficient method for the synthesis of 1-[2-dimethylamino-1-(4-methoxy-phenyl)-ethyl]-cyclohexanol hydrochloride: (±) venlafaxine racemic mixtures
Author/Authors :
Basappa، نويسنده , , C.V. Kavitha، نويسنده , , K.S. Rangappa، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
A novel synthetic method was developed for the synthesis of venlafaxine using inexpensive reagents. An improvement in the method, in the yield was achieved for the conversion of the venlafaxine. This is an improved version, simple and efficient method for the large-scale synthesis of venlafaxine.
Keywords :
condensation , N-methylation , Antidepressants , Venlafaxine , Catalytic reduction.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters