Title of article :
Biological evaluation of substituted quinolines
Author/Authors :
Xavier Franck، نويسنده , , Alain Fournet، نويسنده , , Eric Prina، نويسنده , , Renaud Mahieux، نويسنده , , Reynald Hocquemiller، نويسنده , , Bruno Figadere، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Several quinolines were synthesized and evaluated in vitro against several parasites (Trypanosoma brucei, T. cruzi, Leishmania infantum, L. amazonensis, Plasmodium falciparum). Then, they were evaluated in vitro (at 10 μM), against HTLV-1 transformed cells. A few of them displayed interesting activities, comparable to the reference drugs.
Keywords :
Protozoa , HTLV-1 , Leishmaniases , Trypanozomiases.* Corresponding author. Tel.: +33-01-46-83-55-92 , fax:+33-01-46-83-53-99 , e-mail: bruno.figadere@cep.u-psud.fr
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
