Title of article
Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids as potential DNA-binding agents
Author/Authors
Ahmed Kamal، نويسنده , , O Srinivas، نويسنده , , P Ramulu، نويسنده , , G Ramesh، نويسنده , , P.Praveen Kumar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
4107
To page
4111
Abstract
Pyrrolobenzodiazepine hybrids linked to acridone/acridine ring systems at C8-position have been designed and prepared that exhibit significant DNA-binding affinity, and a representative compound shows promising in vitro anticancer activity.
Keywords
ahmedkamal@ins.iictnet.com , Pyrrolobenzodiazepine , acridone , Acridine , DNA-binding affinity , In vitro anticancer activity.* Corresponding author. Tel.: +91-40-27193157 , fax: +91-40-27193189 , e-mail addresses: ahmedkamal@iict.res.in
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794745
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