Title of article :
Copper dipicolinates as peptidomimetic ligands for the Src SH2 domain
Author/Authors :
Boris Schmidt، نويسنده , , Jan Jiricek، نويسنده , , Alexander Titz، نويسنده , , Guofeng Ye، نويسنده , , Keykavous Parang، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
The introduction of copper chelates into peptide mimetics creates the Src SH2 binding ligands and paramagnetic complexes suitable for EPR studies of peptide protein interactions. The dipicolinic acid was attached to SH2 domain targeting fragments by two different linkers.
Keywords :
Peptide mimetic.* Corresponding author. Tel.: +49-615-1163075 , fax: +49-615-11632-78 , e-mail: schmibo@oc.chemie.tu-darmstadt.de , Copper complex , ESR , SH2 domain
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters