Title of article :
Synthesis of an unusual branched-chain sugar, 5-C-methyl-l-idopyranose for SAR studies of pyranmycins: implication for the future design of aminoglycoside antibiotics
Author/Authors :
Jinhua Wang، نويسنده , , Jie Li، نويسنده , , Przemyslaw G. Czyryca، نويسنده , , Huiwen Chang، نويسنده , , Jeff Kao، نويسنده , , Cheng-Wei Tom Chang، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
The syntheses of a challenging branched-chain sugar and several l-sugars have been accomplished. Their application in studies of the antibacterial activity of pyranmycins is reported, which could provide new strategies for the future design of aminoglycoside antibiotics.
Keywords :
Aminoglycoside antibiotics , Pyranmycins , drug development , Antibacterial.* Corresponding author. Tel.: +1-435-797-3545 , fax: +1-435-797-3390 , e-mail: chang@cc.usu.edu , Branched-chain sugar
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
