Title of article
Synthesis and antibacterial activity of some aryloxy/thioaryloxy oxazolidinone derivatives
Author/Authors
Vishal Arora، نويسنده , , Manikrao M. Salunkhe، نويسنده , , Neelima Sinha، نويسنده , , Rakesh K. Sinha، نويسنده , , Sanjay Jain، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
4647
To page
4650
Abstract
A series of aryloxy/thioaryloxy oxazolidinone derivatives has been synthesized and tested for in vitro antibacterial activity by MIC determination against a panel of susceptible and resistant Gram-positive and Gram-negative microorganisms, some of which are resistant to methicillin and vancomycin. Compounds 12a, 12b, 14a, and 14b from this series were found to be equipotent or more potent than linezolid in vitro.
Keywords
Antibacterial , oxazolidinone , Aryloxy/thioaryloxy derivatives , Resistant bacteria.* Corresponding author. Tel.: +91-20-25126689 , fax: +91-20-25863630 , e-mail addresses: sanjayjain@lupinpharma.com , sanjayjain_ran@hotmail.com
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794847
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