Title of article
Pyridoxine as a template for the design of antiplatelet agents
Author/Authors
Wenlian Zhang، نويسنده , , John Yao، نويسنده , , Vinh Pham، نويسنده , , Tara Whitney، نويسنده , , Doug Froese، نويسنده , , Albert Friesen، نويسنده , , Linda Stang، نويسنده , , Chen Xu، نويسنده , , Ashfaq Shuaib، نويسنده , , James M. Diakur، نويسنده , , Wasim Haque، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
4747
To page
4750
Abstract
The B6 vitamers have been shown to display beneficial therapeutic effects in cardiovascular related disorders. The design of novel antiplatelet agents using pyridoxine as a template has led to the discovery of a class of novel cardio- and cerebro-protective agents. The present study describes the synthesis of several of these derivatives along with the antiplatelet and antiischemic activity of derivative 16.
Keywords
Antiischemic.* Corresponding author. Tel.: +1-204-487-2328 , antiplatelet , e-mail: whaque@canambioresearch.com , Pyridoxine
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794866
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