Author/Authors :
Wenlian Zhang، نويسنده , , John Yao، نويسنده , , Vinh Pham، نويسنده , , Tara Whitney، نويسنده , , Doug Froese، نويسنده , , Albert Friesen، نويسنده , , Linda Stang، نويسنده , , Chen Xu، نويسنده , , Ashfaq Shuaib، نويسنده , , James M. Diakur، نويسنده , , Wasim Haque، نويسنده ,
Abstract :
The B6 vitamers have been shown to display beneficial therapeutic effects in cardiovascular related disorders. The design of novel antiplatelet agents using pyridoxine as a template has led to the discovery of a class of novel cardio- and cerebro-protective agents. The present study describes the synthesis of several of these derivatives along with the antiplatelet and antiischemic activity of derivative 16.
Keywords :
Antiischemic.* Corresponding author. Tel.: +1-204-487-2328 , antiplatelet , e-mail: whaque@canambioresearch.com , Pyridoxine
