Title of article :
5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP
Author/Authors :
Richard Sulsky، نويسنده , , Jeffrey A. Robl، نويسنده , , Scott A. Biller، نويسنده , , Thomas W. Harrity، نويسنده , , John Wetterau، نويسنده , , Fergal Connolly، نويسنده , , Kern Jolibois، نويسنده , , Lori Kunselman، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
5-Carboxamido-1,3,2-dioxaphosphorinanes have been identified as potent inhibitors of microsomal triglyceride-transfer protein. The 1,3,2-dioxaphosphorine functionality acted as a neutral and stable replacement for piperidine and piperidine N-oxide.
Keywords :
MTP inhibitors , e-mail: sulskyr@bms.com , fax: +1 609 8186810 , Cyclophosphonates.* Corresponding author. Tel.: +1 609 8184730
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
