Title of article :
Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands
Author/Authors :
Nilesh Shah، نويسنده , , Thomas S. Scanlan، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
A novel class of phenylpyrazole fused Wieland–Miescher ketone derivatives are high affinity, receptor specific, selective modulators of glucocorticoid receptor (GR) mediated transcription in vitro, dissociating transactivation, AP-1 repression, and NF-κB repression from each other.
Keywords :
Nuclear receptor , Ligand.* Corresponding author. Tel.: +1-4154763620 , Glucocorticoid , fax: +1-4155027220 , e-mail: scanlan@cgl.ucsf.edu
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
