Author/Authors :
Clara Cena، نويسنده , , Donatella Boschi، نويسنده , , Gian Cesare Tron، نويسنده , , Kostantin Chegaev، نويسنده , , Loretta Lazzarato، نويسنده , , Antonella Di Stilo، نويسنده , , Manuela Aragno، نويسنده , , Roberta Fruttero، نويسنده , , Alberto Gasco، نويسنده ,
Abstract :
A new class of NO-donor phenol derivatives is described. The products were obtained by joining appropriate phenols with either nitrooxy or 3-phenylsulfonylfuroxan-4-yloxy moieties. All the compounds proved to inhibit the ferrous salt/ascorbate induced lipidic peroxidation of membrane lipids of rat hepatocytes. They were also capable of dilating rat aorta strips precontracted with phenylephrine.
Keywords :
Phenol antioxidants , nitric oxide , NO donors , NO-donorphenol antioxidants.
