Title of article
Discovery of a novel, potent and selective human β3-adrenergic receptor agonist
Author/Authors
Yutaka Nakajima، نويسنده , , Hitoshi Hamashima، نويسنده , , Ken-ichi Washizuka، نويسنده , , Yasuyo Tomishima، نويسنده , , Hiroaki Ohtake، نويسنده , , Emiko Imamura، نويسنده , , Toshiko Miura، نويسنده , , Hiroshi Kayakiri، نويسنده , , Masayuki Kato، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
251
To page
254
Abstract
The discovery of a novel, potent and selective β3-adrenergic receptor (AR) agonist is described. SAR studies demonstrated the structural requirements for activity and selectivity. Compound 1c, which showed good β3-AR activity and selectivity, was identified and pharmacokinetics were investigated.
Keywords
?3-Adrenergic receptor agonist
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795186
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