Title of article
Pyrimidine containing RSV fusion inhibitors
Author/Authors
Antonia Nikitenko، نويسنده , , Yuri Raifeld، نويسنده , , Boris Mitsner، نويسنده , , Howard Newman، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
427
To page
430
Abstract
The knowledge of SAR in a series of biphenyl anionic RSV inhibitors has been broadened by synthesis and testing of analogs with pyrimidine linkers. Generally, pyrimidine compounds were much harder to synthesize, and their anti-RSV activity was lower in comparison with triazine analogs.
Keywords
respiratory syncytial virus , nucleophilic substitution , Fusion inhibition , Trichloropyrimidine
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795219
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