Title of article
Syntheses of 2,4,6-trisubstituted triazines as antimalarial agents
Author/Authors
Anu Agarwal، نويسنده , , Kumkum Srivastava، نويسنده , , S.K. Puri، نويسنده , , Prem M.S. Chauhan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
3
From page
531
To page
533
Abstract
A series of 2,4,6-trisubstituted-1,3,5-triazines (2a–s) were synthesized and evaluated for their in vitro antimalarial activity against P. falciparum. Out of the 19 compounds synthesized eight compounds showed MIC in the range of 1–2 μg/mL. These compounds are in vitro several times more active than cycloguanil.
Keywords
Antimalarial , DHFR , triazine
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795237
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