• Title of article

    New conformationally locked bicyclic N,O-nucleoside analogues of antiviral drugs

  • Author/Authors

    Antonio Procopio، نويسنده , , Stefano Alcaro، نويسنده , , Antonio De Nino، نويسنده , , Loredana Maiuolo، نويسنده , , Francesco Ortuso، نويسنده , , Giovanni Sindona، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    6
  • From page
    545
  • To page
    550
  • Abstract
    In order to obtain rigidity within the sugar moiety of nucleosides, the bicyclic pyrimidine derivatives of N,O-isoxazolidines were designed and synthesized by using 1,3-dipolar cycloaddition of Δ1-pyrrolidine-1-oxide and the appropriate vinyl-nucleobases.
  • Keywords
    N , Vinylpyrimidine nucleobases , O-Isoxazolidines , Nucleoside analogues
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    795240