Inclusion complexes of N-sulfamoyloxazolidinones with β-cyclodextrin

A study of inclusion complexes of six N-sulfamoyloxazolidinone derivatives with β-cyclodextrin is described. The inclusion complexes were prepared in solution and in solid state with stoichiometry host–guest 1:1, and characterized. In solution, the complexation was carried out by spectrophotometric measurements at 25 °C. The stoichiometries and stability constants of complexes at various pHs have been determined using second-derivative spectrophotometry UV–vis. Hydrophobic properties of N-sulfamoyloxazolidinones are improved following their inclusion into β-CD.