Title of article
(R)-2-(4-Phenylbutyl)dihydrobenzofuran derivatives as melatoninergic agents
Author/Authors
Li-Qiang Sun، نويسنده , , Katherine Takaki، نويسنده , , Jie Chen، نويسنده , , Stephen Bertenshaw، نويسنده , , Lawrence Iben، نويسنده , , Cathy D. Mahle، نويسنده , , Elaine Ryan، نويسنده , , Dedong Wu، نويسنده , , Qi Gao، نويسنده , , Cen Xu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
5
From page
1345
To page
1349
Abstract
(R)-2-(4-Phenylbutyl)dihydrobenzofuran derivatives (e.g., 3 and 4) were synthesized as novel melatoninergic ligands with significantly lower vasoconstrictive activity in vitro in the rat tail artery. Binding affinity assays were performed on cloned human MT1 and MT2 receptors stably expressed in NIH3T3 cells.
Keywords
Melatoninergic agents , dihydrobenzofuran , melatonin , Melatonin Receptors
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795393
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