Title of article :
Design, synthesis and biological evaluation of novel bicyclic β-lactams as potential antimalarials
Author/Authors :
Manisha Nivsarkar، نويسنده , , D. Thavaselvam، نويسنده , , C. S. Prasanna Kumar، نويسنده , , Mamta Sharma، نويسنده , , M.P. Kaushik، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A series of bicyclic N-substituted and unsubstituted β-lactams were synthesized and evaluated as targeted potential antimalarials. The compounds MNR4 and MNR5 were found to have highest potency against Plasmodium falciparum in vitro.
Keywords :
Plasmodium falciparum , bicyclic , Antimalarial , ?-lactam
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
