Title of article :
Novel jadomycins: incorporation of non-natural and natural amino acids
Author/Authors :
David L. Jakeman، نويسنده , , Spring Farrell، نويسنده , , Wendy Young، نويسنده , , René J. Doucet، نويسنده , , Shannon C. Timmons، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Electrospray ionization mass spectrometry of extracts from Streptomyces venezuelae ISP5230 cultures grown on chemically synthesized non-natural l-amino acids, d-amino acids or any of the 20 natural amino acids demonstrated incorporation of the amino acid into a jadomycin B analogue.
Keywords :
Aldimine intermediates , Biosynthesis , Angucycline antibiotics , Combinatorial secondary metabolites
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
