Title of article :
3H-Quinazolin-4-ones as a new calcilytic template for the potential treatment of osteoporosis
Author/Authors :
Irina Shcherbakova، نويسنده , , Manuel F. Balandrin، نويسنده , , John Fox، نويسنده , , Anjan Ghatak، نويسنده , , William L. Heaton، نويسنده , , Rebecca L. Conklin، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Structure–activity relationship studies, focused on identification of the active pharmacophore fragments in a single high-throughput screening calcilytic hit, resulted in the discovery of potent calcium receptor antagonists, substituted 3H-quinazolin-4-ones.
Keywords :
3H-Quinazolin-4-ones , osteoporosis , Calcilytics , Calcium receptor antagonists
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
