• Title of article

    3H-Quinazolin-4-ones as a new calcilytic template for the potential treatment of osteoporosis

  • Author/Authors

    Irina Shcherbakova، نويسنده , , Manuel F. Balandrin، نويسنده , , John Fox، نويسنده , , Anjan Ghatak، نويسنده , , William L. Heaton، نويسنده , , Rebecca L. Conklin، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    1557
  • To page
    1560
  • Abstract
    Structure–activity relationship studies, focused on identification of the active pharmacophore fragments in a single high-throughput screening calcilytic hit, resulted in the discovery of potent calcium receptor antagonists, substituted 3H-quinazolin-4-ones.
  • Keywords
    3H-Quinazolin-4-ones , osteoporosis , Calcilytics , Calcium receptor antagonists
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    795434