Title of article :
Synthesis of 15R-PGD2: a potential DP2 receptor agonist
Author/Authors :
Seongjin Kim، نويسنده , , Sophie Bellone، نويسنده , , Kirk M. Maxey، نويسنده , , William S. Powell، نويسنده , , Gue-Jae Lee، نويسنده , , Joshua Rokach، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
The first total synthesis of 15R-PGD23 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE2. 15R-PGD2, a potential DP2 receptor agonist, could be an important novel tool for defining the role of this receptor in inflammatory diseases.
Keywords :
15R-PGD2 , DP2 receptor , 15R-PGE2 , eosinophils , Prostaglandin D2
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
