مرکز منطقه ای اطلاع رساني علوم و فناوري - Design, synthesis and activity of novel derivatives of Oxybutynin and Tolterodine

Title of article :

Design, synthesis and activity of novel derivatives of Oxybutynin and Tolterodine

Author/Authors :

Kirandeep Kaur، نويسنده , , Shelly Aeron، نويسنده , , Miriyala Bruhaspathy، نويسنده , , Shankar J. Shetty، نويسنده , , Suman Gupta، نويسنده , , Laxminarayan H. Hegde، نويسنده , , Arun D.V. Silamkoti، نويسنده , , ANITA MEHTA، نويسنده , , Anita Chugh، نويسنده , , Jang B. Gupta، نويسنده , , P.K.S. Sarma، نويسنده , , Naresh Kumar، نويسنده ,

Issue Information :

روزنامه با شماره پیاپی سال 2005

Pages :

From page :

2093

To page :

2096

Abstract :

Novel derivatives of Tolterodine (1) and Oxybutynin (2) have been designed using conformationally restricted azabicyclics as replacement for open-chain amines. The synthesis and structure–activity relationships are presented.

Keywords :

oxybutynin , Tolterodine , Azabicyclohexane , elective muscarinic antagonists

Journal title :

Bioorganic & Medicinal Chemistry Letters

Serial Year :

2005

Journal title :

Bioorganic & Medicinal Chemistry Letters

Record number :

795538

Link To Document :

https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=795538