Title of article
Synthesis and antifungal activity of 5-arylamino-4,7-dioxobenzo[b]thiophenes
Author/Authors
Chung-Kyu Ryu، نويسنده , , Su-Kyung Lee، نويسنده , , Ja-Young Han، نويسنده , , Ok-Jai Jung، نويسنده , , Jung Yoon Lee، نويسنده , , Seong Hee Jeong، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
2617
To page
2620
Abstract
5-Arylamino-4,7-dioxobenzo[b]thiophenes 3–6 were synthesized and tested for in vitro antifungal activity against Candida and Aspergillus species. 5-Arylamino-6-chloro-2-(methoxycarbonyl)-4,7-dioxobenzo[b]thiophenes 5 showed, in general, more potent antifungal activity against Candida species than the other 4,7-dioxobenzo[b]thiophenes 3, 4 and 6. The results suggest that 5-arylamino-4,7-dioxobenzo[b]thiophenes would be potent antifungal agents.
Keywords
Antimicrobial compounds , fungi , 4 , substitution effects , antifungal
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795638
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