Title of article :
A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes
Author/Authors :
Sharon N. Bisaha، نويسنده , , Mary F. Malley، نويسنده , , Andrew Pudzianowski، نويسنده , , Hossain Monshizadegan، نويسنده , , Paulina Wang، نويسنده , , Cort S. Madsen، نويسنده , , Jack Z. Gougoutas، نويسنده , , Philip D. Stein، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
3
From page :
2749
To page :
2751
Abstract :
The preferred absolute configuration of two series of F1F0-ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in each series is different, each series presents the same ‘triaryl’ pharmacophore to the enzyme binding site.
Keywords :
Mitochondrial ATPase , Acylguanidine , Chiral synthesis
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2005
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
795663
Link To Document :
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