• Title of article

    Synthesis of substituted indole derivatives as a new class of antimalarial agents

  • Author/Authors

    Anu Agarwal، نويسنده , , Kumkum Srivastava، نويسنده , , S.K. Puri، نويسنده , , Prem M.S. Chauhan، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    3133
  • To page
    3136
  • Abstract
    A series of substituted indole derivatives were synthesized and evaluated for their in vitro antimalarial activity against P. falciparum. Out of the 24 compounds synthesized six compounds have shown MIC of 1 μg/mL. These compounds are in vitro several folds more active than pyrimethamine.
  • Keywords
    Antimalarial , dihydrofolate reductase , Pyrimidine
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    795741

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=795741