Title of article
Anxiolytic effects of benzalphthalides
Author/Authors
Alejandro Zamilpa، نويسنده , , Maribel Herrera-Ruiz، نويسنده , , Esther del Olmo، نويسنده , , José L. L?pez-Pérez، نويسنده , , Jaime Tortoriello، نويسنده , , Arturo San Feliciano، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
3483
To page
3486
Abstract
Anxiolytic effects induced by benzalphthalides on mice have been evaluated. The evaluation was based on the spent time and the number of entries of animals into the open arms in the elevated plus maze test. Single administration of benzalphthalides 1 and 11 induced significant increments in both parameters, thus revealing their potentiality as new leads for the development of non-benzodiazepinic and non-nitrogenated antianxiety agents.
Keywords
Benzalphthalides , anxiolytic effect , SAR , Apigenin , diazepam
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795815
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