Interaction of chiral MS-245 analogs at h5-HT6 receptors
Author/Authors :
Carmen Abate، نويسنده , , Renata Kolanos، نويسنده , , Malgorzata Dukat، نويسنده , , Vince Setola، نويسنده , , Bryan L. Roth، نويسنده , , Richard A. Glennon، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
4
From page :
3510
To page :
3513
Abstract :
Optically active pyrrolidinylmethylindole analogs related in structure to the benzenesulfonyltryptamine 5-HT6 receptor antagonist MS-245 were evaluated and their R-isomers were found to bind with affinity higher than their S-enantiomers.