Title of article
Lp-PLA2 inhibitory activities of fatty acid glycerols isolated from Saururus chinensis roots
Author/Authors
Woo Song Lee، نويسنده , , Mi-Jeong Kim، نويسنده , , Young-Il Beck، نويسنده , , Yong-Dae Park، نويسنده , , Tae-Sook Jeong، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
3
From page
3573
To page
3575
Abstract
(R)-Glycerol-monolinoleate 4 and (R)-glycerol-monostearate 5 were isolated from the ethyl acetate extracts of Saururus chinensis roots and (R)- or (S)-fatty acid glycerols 4 and 5 were synthesized for confirming their structures and evaluating their inhibitory activities against Lp-PLA2. The (R)-4 and (S)-4 exhibited Lp-PLA2 inhibitory activities with IC50 values of 45.0 and 52.0 μM, respectively.
Keywords
Lp-PLA2 inhibitor , Fatty acid glycerols , Saururus chinensis
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795835
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