Title of article
Synthesis of novel curcumin mimics with asymmetrical units and their anti-angiogenic activity
Author/Authors
Ho Bum Woo، نويسنده , , Woon-Seob Shin، نويسنده , , Seokjoon Lee، نويسنده , , Chan Mug Ahn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
5
From page
3782
To page
3786
Abstract
Novel curcumin mimics with asymmetrical units phenyl group with alkyl amide, chloro-substituted benzamide, or heteroaromatic amide moieties were synthesized and their anti-angiogenic activity was evaluated with the proliferation and tube formation inhibitory activity on the human umbilical vein endothelial cells. Compounds 5, 14, 17, and 18 showed potent growth inhibitory activity and tube formation inhibitory activity.
Keywords
Curcumin , Heteroaromatic amides , Anti-angiogenic activity
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795880
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