• Title of article

    Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1

  • Author/Authors

    Xiaoyan Zhang، نويسنده , , Maud Urbanski، نويسنده , , Mona Patel، نويسنده , , Roxanne E. Zeck، نويسنده , , Geoffrey G. Cox، نويسنده , , Haiyan Bian، نويسنده , , Bruce R. Conway، نويسنده , , Mary Pat Beavers، نويسنده , , Philip J. Rybczynski، نويسنده , , Keith T. Demarest، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    5
  • From page
    5202
  • To page
    5206
  • Abstract
    A series of benzo-fused heteroaryl-O-glucosides was synthesized and evaluated in SGLT1 and 2 cell-based functional assays. Indole-O-glucoside 10a and benzimidazole-O-glucoside 18 exhibited potent in vitro SGLT2 inhibitory activity.
  • Keywords
    Heteroaryl-O-glucosides , SGLT
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    796156