Title of article :
Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1
Author/Authors :
Xiaoyan Zhang، نويسنده , , Maud Urbanski، نويسنده , , Mona Patel، نويسنده , , Roxanne E. Zeck، نويسنده , , Geoffrey G. Cox، نويسنده , , Haiyan Bian، نويسنده , , Bruce R. Conway، نويسنده , , Mary Pat Beavers، نويسنده , , Philip J. Rybczynski، نويسنده , , Keith T. Demarest، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
5
From page :
5202
To page :
5206
Abstract :
A series of benzo-fused heteroaryl-O-glucosides was synthesized and evaluated in SGLT1 and 2 cell-based functional assays. Indole-O-glucoside 10a and benzimidazole-O-glucoside 18 exhibited potent in vitro SGLT2 inhibitory activity.
Keywords :
Heteroaryl-O-glucosides , SGLT
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2005
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
796156
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=796156
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