Title of article :
Anti-malarial activity of Baylis–Hillman adducts from substituted 2-chloronicotinaldehydes
Author/Authors :
P. Narender، نويسنده , , U. Srinivas، نويسنده , , B. Gangadasu، نويسنده , , Sukla Biswas، نويسنده , , M. Janaki Ram Reddy and V. Jayathirtha Rao، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
New Baylis–Hillman adducts are synthesized based on substituted 2-chloronicotinaldehydes and screened for their in vitro anti-malarial activity against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. Out of the six new compounds synthesized and screened, 2b, 2c and 2d compounds showed substantial anti-malarial activity.
Keywords :
Substituted 2-chloronicotinaldehydes , Baylis–Hillman adducts , Anti-malarial activity
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
