Title of article
Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases
Author/Authors
Weitao Pan، نويسنده , , Hu Liu، نويسنده , , Yong-Jiang Xu، نويسنده , , Xin Chen، نويسنده , , Ki-Hwan Kim، نويسنده , , Daniel L. Milligan، نويسنده , , John Columbus، نويسنده , , Yaron R. Hadari، نويسنده , , Paul Kussie، نويسنده , , Wai C. Wong، نويسنده , , Marc Labelle، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
5474
To page
5477
Abstract
Pyrimido-oxazepine based sub-micromolar inhibitors (2–4) for Aurora and FLT-3 were designed and synthesized. These preliminary results supported the potential use of pyrimido-oxazepines as a versatile template for developing specific kinase inhibitors.
Keywords
Kinase inhibitor , Oxazepine , Aurora , FLT-3
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796211
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