Title of article :
Scaffold oriented synthesis. Part 1: Design, preparation, and biological evaluation of thienopyrazoles as kinase inhibitors
Author/Authors :
Irini Akritopoulou-Zanze، نويسنده , , Daria Darczak، نويسنده , , Kathy Sarris، نويسنده , , Kathleen M. Phelan، نويسنده , , Jeffrey R. Huth، نويسنده , , Danying Song، نويسنده , , Eric F. Johnson، نويسنده , , Yong Jia، نويسنده , , Stevan W. Djuric، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
4
From page :
96
To page :
99
Abstract :
We report the synthesis of kinase targeted libraries based on the thienopyrazole scaffold. Several thienopyrazole analogs have been identified as submicromolar inhibitors of KDR.
Keywords :
Kinase inhibitors , Thienopyrazoles , Targeted libraries , KDR inhibitors , De novo design
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2006
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
796321
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=796321
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