Title of article
Two methylene groups in phospholipids distinguish between apoptosis and necrosis for tumor cells
Author/Authors
Hideaki Nagami، نويسنده , , Koji Nakano، نويسنده , , Hideaki Ichihara، نويسنده , , Yoko Matsumoto، نويسنده , , Ryuichi Ueoka، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
782
To page
785
Abstract
High inhibitory effects of hybrid liposomes (HL) themselves composed of DMPC/10 mol % C12(EO)23 on the growth of HL-60 cells were obtained without any drug. Induction of apoptosis was obtained by the HL of DMPC/10 mol % C12(EO)23. On the other hand, necrosis was observed for the HL of DLPC/10 mol % C12(EO)23. In the case of DPPC/10 mol % C12(EO)23, neither apoptosis nor necrosis was observed.
Keywords
Liposome , phospholipid , Antitumor effect , Apoptosis
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796459
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